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投稿时间：2025-05-25
投稿时间：2025-05-25
中文摘要: 该文以黄精、枸杞为主要原料，制备黄精枸杞凝胶软糖，以感官评分为评价指标，通过单因素试验和响应面试验优化制备工艺，并考察黄精枸杞多糖的降血糖作用。结果表明，黄精枸杞凝胶软糖最佳配方为赤藓糖醇添加量20%、凝胶添加量5%、胶体复配比8∶2（卡拉胶与魔芋胶质量比）、黄精枸杞多糖添加量4%，此条件下感官评分为58。动物实验结果表明，与模型对照组相比，黄精枸杞多糖低、中剂量组空腹血糖（fasting blood glucose，FBG）水平分别显著下降19.57%、12.81%（P<0.05），各剂量组糖化血清蛋白（glycosylated serum protein，GSP）水平、胰岛素抵抗指数（homeostatic model assessment of insulin resistance，HOMA-IR）和胰岛素水平均明显下降。胰腺组织病理学分析结果表明，黄精枸杞多糖可缓解胰腺组织损伤。
Abstract:Polygonati Rhizoma and Lycii Fructus were used as main materials to prepare Polygonati Rhizoma-Lycii Fructus gummy candy.With sensory score as the indicator,single-factor experiments and response surface methodology were employed to optimize the preparation process.The blood glucose-lowering effects of the prepared gummy candy were then evaluated.The optimal formula for Polygonati Rhizoma-Lycii Fructus gummy candy was determined as follows：20% erythritol,5% gel（carrageenan gum：konjac glucomannan mass ratio=8∶2）,and 4% Polygonati Rhizoma-Lycii Fructus polysaccharides.The gummy candy prepared with the optimal formula achieved a sensory score of 58.Animal experiments showed that compared with the model group,the low-and medium-dose Polygonati Rhizoma-Lycii Fructus polysaccharide groups showed fasting blood glucose（FBG）reductions of 19.57%、12.81%,respectively（P<0.05）.All dose groups exhibited significant decreases in glycosylated serum protein（GSP）,homeostatic model assessment of insulin resistance（HOMAIR）,and insulin levels,along with alleviated pancreatic tissue damage.
keywords: Polygonati Rhizoma polysaccharide Lycii Fructus polysaccharide process optimization gummy candy lowering blood glucose
文章编号：202605005 中图分类号： 文献标志码：
基金项目:四川大学-达州校市合作专项资金项目（2022CDDZ-19）；阿坝州应用技术研究与开发基金项目（R23YYJSYJ0025）；四川省科技厅“三区”人才支持计划科技人员专项计划项目（川科农（2021）17号）
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