Abstract:With the aim of expanding the application of cellulose nanocrystals in food， the cellulose nanocrystal-sodium alginate gel particles and cellulose nanocrystal-sodium alginate-whey protein isolate micro/nano particles loaded with curcumin for lowering lipid levels were developed with sodium alginate as the main body of the gel and cellulose nanocrystals as the raw materials. After the addition of cellulose nanocrystals， the water retention， gel strength， and storage stability of sodium alginate gel particles were improved. Coupling curcumin， which possessed antioxidant activity， endowed cellulose nanocrystals with lipid-lowering activity and certain antioxidant activity. On this basis， the two types of particles prepared also had certain glucose adsorption capacity and antioxidant capacity. Compared with cellulose nanocrystals， cellulose nanocrystal gel particles and micro/nano particles decreased the intestinal fat transport， thereby reducing the fat absorption of mice. In conclusion， cellulose nanocrystal gel particles and micro/nano particles can well preserve the lipidlowering activity of cellulose nanocrystals.