Abstract:With the increasing demand for food safety and quality，safe，nontoxic，and efficient natural food preservatives have become a research focus in the food industry. Marine microorganisms，due to their unique survival environments，can produce natural products with complex chemical structures and diverse biological activities，showing great potential in the field of food preservation. This study reviewed the types，biological activities，and food preservation mechanisms of marine microbial natural products，and it discussed the prospects and challenges in the application of the products，so as to provide a reference for further research and application of marine microbial natural products in food preservation.