本文已被：浏览 1204次 下载 1633次
投稿时间：2023-11-28
投稿时间：2023-11-28
中文摘要: 以金银花粉为主要原料，采用D-最优混料设计对金银花泡腾片混料进行优选，计算金银花泡腾片相关指标权重系数并对其进行综合评价。以金银花泡腾片的崩解时限、起泡性、感官评价作为评价指标，采用基于主观的层次分析（analytic hierarchy process，AHP）法、基于指标相关性的指标权重分析（criteria importance through intercriteria correlation，CRITIC）法和AHP-CRITIC 复合加权法，通过计算指标的权重系数，分析比较单一和复合的赋权法结果，并利用傅里叶变换红外光谱（Fourier transform infrared spectroscopy，FTIR）对D-最优混料设计优化金银花泡腾片进行结构表征。结果表明，以AHP-CRITIC 复合加权法得到的金银花泡腾片，崩解时限、起泡性和感官评分的复合权重系数分别是0.261、0.227 和0.512；经D-最优混料设计优化得到的最优金银花泡腾片配方为金银花浸膏粉含量为23.40%、乳糖含量为34.40%、崩解剂含量为37.20%、聚乙二醇6000（polyethylene glycol 6000，PEG6000）含量为5%；通过红外光谱图发现金银花泡腾片中多酚与绿原酸等有效成分存在。
中文关键词: 金银花泡腾片 D-最优混料设计 层次分析（analytic hierarchy process，AHP）法 基于指标相关性的指标权重分析（criteria importance through intercriteria correlation，CRITIC）法 AHP-CRITIC 复合加权法
Abstract:The weight coefficients of relevant indicators of honeysuckle effervescent tablets were calculated，and the D-optimal mixture design was employed to optimize the formula of honeysuckle effervescent tablets.Furthermore，the produced honeysuckle effervescent tablets were comprehensively evaluated.The disintegration time limit，effervescence，and sensory quality of honeysuckle effervescent tablets were used as evaluation indicators，and the weight coefficient of each indicator was calculated by the analytic hierarchy process（AHP）method，criteria importance through intercriteria correlation（CRITIC）method，and the AHP-CRITIC composite weighting method.The results obtained by single and composite weighting methods were compared.The formula of honeysuckle effervescent tablets was optimized by the D-optimal mixture design，and the prepared tablets were structurally characterized by Fourier transform infrared spectroscopy（FTIR）.The results showed that the AHP-CRITIC composite weighting method was more comprehensive and reasonable than the single weighting methods.The weighting coefficients of the disintegration time limit，effervescence，and sensory quality of honeysuckle effervescent tablets obtained by the AHP-CRITIC composite weighting method were 0.261，0.227，and 0.512，respectively.The optimal formula of honeysuckle effervescent tablets was composed of 23.40% honeysuckle extract powder，34.40% lactose，37.20% disintegrant，and 5% polyethylene glycol 6000.The FTIR results indicated the existence of polyphenols and chlorogenic acid in honeysuckle effervescent tablets.
keywords: honeysuckle effervescent tablets D-optimal mixture design analytic hierarchy process（AHP） criteria importance through intercriteria correlation（CRITIC） AHP-CRITIC composite weighting method
文章编号：202415018 中图分类号： 文献标志码：
基金项目:郑州工程技术学院2022 年度技术研发推广与转化基金项目（zjz202203）；河南省高等学校重点科研计划项目（22B550020）
| Author Name | Affiliation |
| WANG Lan，WANG Mengying，WANG Limin*，NIE Hui* | School of Food Science&Chemical Engineering，Zhengzhou University of Technology，Zhengzhou 450044，Henan，China |
引用文本：
津ICP备20000603号-1