Abstract:Musalais is a kind of traditional drink with ethnic characteristics of Xinjiang.This study intended to establish a gas chromatography method for the simultaneous determination of methanol and ethanol.The analytical conditions of the method were as follows:the temperature of the injector was 250℃，the temperature of the detector was 250 ℃，the injection volume was 1 μL，the split ratio was 50∶1，the programmed temperature was raised to 120℃for 2 min，and the rate of 10℃/min was raised to 170℃for 3 min.In this method，methanol and alcohol were separated from each other completely，a good linearity was achieved，the detection limits of methanol and alcohol were 2.34 mg/L and 0.05%，the recovery of methanol and alcohol ranged from 93.18% to 97.66%，the relative standard deviation methanol and alcohol were 2.39% and 1.71% （n=6）.The method had the advantages of simple operation，high sensitivity，good reproducibility and short analysis time.It was suitable for the simultaneous determination of methyl alcohol and ethanol in Musalais.