Abstract:Oenococcus oeni is the main lactic acid bacteria species associated with grapes and wine.It is an auxotrophic bacterium that can survive the harsh conditions of wine，plays a major role in wine malolactic fermentation，and is the shaper of the final flavor of wine.In order to further improve the application of O.oeni in the wine brewing industry，the article isolated，screened and identified O.oeni strains，as well as evaluated the beneficial effects they had on winemaking，the influence of the winemaking process on O.oeni，and the molecular biology of O.oeni.Herein，the research progress was summarized.