Abstract:Time-resolved fluorescence analysis is a technique to detect the change of fluorescence with time at fixed wavelength.It uses lanthanide and its complexes as fluorescent markers.It has the characteristics of high efficiency，high specificity and high sensitivity because of this principle.Because of the accumulation toxicity and high carcinogenicity of some low concentration pollutants in food，the sensitivity of the detection method is very high，and the time-resolved fluorescence analysis technology can meet the requirements of high sensitivity in the detection of these pollutants.This paper introduced the principle and characteristics of this technology and summarized its application in food contamination detection.