Abstract:Both Chenopodium formosanum and Fagopyrum esculentum Moench.are medicinal and edible homologous plants with a long history and high nutritional value，which have the effects of anti-oxidation，antiinflammation，anti-glycation and so on.In the glycation injury cell model cultured in vitro，the extract of Chenopodium formosanum and Fagopyrum esculentum Moench.could increase the content of collagen and scavenge oxygen free radicals effectively.After 6 weeks of drinking the fruit-flavored drink with Chenopodium formosanum and Fagopyrum esculentum Moench.extracts as the main functional raw material.It was found that the facial skin moisture content，skin gloss，skin color L*value and b*value，as well as the depth of wrinkles in the canthus，were significantly improved.Based on the above data，it was found that，as a beauty-efficient drink with skin improvement，its main efficacy raw materials and drinks have better antioxidant，anti-glycation and other effects，and there were no adverse reactions in human trials.