Abstract:On the basis of single-factor test，the response surface methodology was used to investigate the effects of processing parameters，including solvent concentration，temperature，extraction time and ultrasound power.The extraction rate of GPM polyphenols was chosen as response value，mathematical model was established by implementing four factors and three levels at the basic of Box-Behnken design.The optimum technological conditions were 55%aqueous ethanol concentration，ultrasonic temperature of 70℃，extraction time of 53 min and ultrasonic power of 106 W.Under the optimum conditions，the yield rate of polyphenol was 0.522%，which general accorded with the predicted value（0.524%）according to the modal.