Abstract:To preparing drug loaded samples，the cabbage was soaked in imidacloprid and acetamiprid aqueous solution， simulated farmers use pesticide scenarios， with all kinds of cleaning methods for loading samples， measured by HPLC， calculation of imidacloprid and acetamiprid residue removal rate， loss of simultaneous de－ termination of vitamin C. The results showed that different temperature water immersion can remove part of imi－ dacloprid and acetamiprid residues， but the removal rate and water temperature changes was no positive corre－ lation between. On the basis of soaking， supplemented by churning， ozone， add detergent can improve the cab－ bage in imidacloprid and acetamiprid removal rate， detergent removal rate was the highest， but taking into ac－ count the residue in food and vitamin C losses was not recommended use detergent to wash. Ultrasonic cleaning on cabbage in imidacloprid and acetamiprid removal rate and vitamin C loss ratio and ultrasonic time does not have a positive correlation.