Abstract:Molecular imprinting has received：considerable attention recently due to its properties of selective recognition，easy preparation，good reproducibility and stability.Quantum dots as a fluorescent nanomaterial have unique optical properties.An optosensing system is prepared based on molecularly imprinted polymers and quantum dots，which are used as the recognition elements and response elements，respectively，for rapid and accurate detection of hazardous residues in foods.In this review，we summarized the characteristic of quantum dots and molecular imprinting，the preparation of optosensing system，as well as the application in the field of food safety.