Abstract:Siraitia grosvenorii is the ripe friut of perennial liana Siraitia grosvenorii Swingle.Some studies indicated that Siraitia grosvenorii had a better effect of lowering blood suger value，and the active componet on hpyerglycemic was mainly including the mogroside，flavones，polysaccharide.Siraitia grosvenorii lower blood glucose by restoring the pancreas injury and promoting the secretion of insulin，lipid-lowering，scavenging free radicals and anti-lipid peroxidation and inhibiting the activity of α-glucosidase．In this review，the research of the active component on hpyerglycemic was expounded.In addition，the mechanism of action on hpyerglycemic was illuminated.At last，future perspective for Siraitia grosvenorii research was put forward.