Abstract:A method was developed for determination of 17 phthalate esters residues in drinks using QuEChERS and gas chromatography-tandem mass spectrometry（GC/MS/MS）.The samples were extracted with n-hexane and cleaned up with dispersive-solid phase extraction.The extracts were determined by GC/MS/MS using external standard method.The linearity of the method was good between 5 μg/L and 1000 μg/L.In milk beverage，the mean recoveries at the three spiked levels of 10，50，200 μg/kg were 80.9%-108.7%，the relative standard deviation（RSD）were 0.2%-14.2%.In fruit drink，the mean recoveries at the three spiked levels of 10，50，200 μg/kg were 81.4%-110.2%，the relative standard deviation（RSD）were 1.3%-13.0%.The detection limits and quantitation limits were 1.5 μg/kg-3.0 μg/kg and 5.0 μg/kg-10.0 μg/kg respectively.The simplicity，sensitivity and good precision of the method made it be well suitable for determination of phthalate esters residues in drinks.