Abstract:Crystallization conditions of lactitol were optimized. Firstly， the optimized condition of each factor was investigated. Then， after orthogonal tests， the optimized crystallization conditions were obtained as： the concentration of lactose was 95 %， crystallization temperature was 70 ℃， the cooling speed was 1 ℃/h， stirring speed was 150 r/min， under the above conditions， the crystallization yield of lactitol reached 45.91 % ， the content of lactitol in the dry matter reached 99.71 %.