Abstract:In order to study the hypoglycemic effect of compound tea，the inhibitory activity of α-glucosidase was used as an indicator to study the inhibitory activity of corn silk and kudzu root compound tea and its 5 individual components. The results showed that compound tea and its individual components have inhibitory effects on α-glucosidase，with kudzu root and gardenia having the most significant inhibition rates，with halfinhibition concentrations of 1.87 mg/mL and 1.32 mg/mL respectively. Further research found that as the concentration of compound tea extract increases，the michaelis constant （Km） and maximum velocity （Vmax） of the enzymatic reaction decreases，indicating that it has a reversible mixed-type inhibition on α-glucosidase. Animal experiments showed that the fasting blood glucose value and postprandial blood glucose of the high and low dose groups were lower than those of the model group after gavage，Indicating corn silk and kudzu root compound tea has a hypoglycemic effect and has the potential to be developed into a sugar-lowering functional food.