Abstract:Green tea，kale and konjac fine powder were used as main raw materials to develop a lipid-lowering compound meal replacement powder.The formulation was optimized through the single-factor test and the orthogonal test，and the principal component analysis（PCA）was used to evaluate the antioxidant activity and in vitro lipid-lowering efficacy of the meal replacement powder.The results showed that the optimal formulation of green tea compound meal replacement powder was obtained as follows：green tea of 20%，kale of 45%，konjac fine powder of 1.5%，and other components of 33.5%.Under the above formulation，this meal replacement powder had good solubility，delicate taste，coordinated aroma，comprehensive nutrients，low energy and fat content，rich proteins，and excellent antioxidant activity and in vitro lipid-lowering efficacy，and can be used as a dietary choice for obese people.