Abstract:With the activities of selenium and polysaccharide，selenium polysaccharide is a new type of selenium dietary supplement.In recent years，there has been an explosion of research on the structure and biological activities of this compound.However，due to the complex structure and the limited synthesis methods，no systematic summary on this compound is available.This paper reviews the extraction and purification of selenium polysaccharides，structure characterization of polysaccharides selenized with different methods，binding of selenium and polysaccharides，and the biological activities of selenium polysaccharides in vivo and in vitro，which is expected to provide a reference for the in-depth research on selenium polysaccharides and the development and utilization of related products.