Abstract:Using licorice as raw material，using ultrasonic-assisted eutectic solvent method，the effects of eutectic solvent types，molar ratio，water content，extraction temperature，material-liquid ratio，ultrasonic time，ultrasonic power on the extraction rate of glycyrrhizin polysaccharide were studied，and through the design of response surface experiment，the technological conditions for extracting polysaccharides from licorice were optimized.The results showed that the choline chloride-isopropanol system with a water content of 40% and a molar ratio of 1∶3 was used as the extractant.The extraction temperature was 39℃，the material-liquid ratio was 1∶50（g/mL），the ultrasonic time was 30 min，and the ultrasonic power 250 W，the extraction rate of polysaccharide reached 8.31%.