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投稿时间:2020-01-10
投稿时间:2020-01-10
中文摘要: 以海藻酸钠为壁材,黑米花色苷提取物为芯材,利用微胶囊造粒机制备花色苷微胶囊。以花色苷包埋率为指标,考察壁芯比、喷头孔径、海藻酸钠浓度和氯化钙浓度对花色苷包埋率的影响,得到最佳工艺参数:壁芯比为3∶1、喷头孔径为0.45 mm、海藻酸钠浓度为4.0%、氯化钙浓度为3.0%。同时考察黑米花色苷微胶囊的缓释性质以及稳定性。结果证明花色苷微胶囊化后,在胃模拟液中,花色苷微胶囊在4.0 h内可以保持低释放率,进入肠道模拟液中实现释放。稳定性研究证明,花色苷微胶囊化后仍需要隔绝空气和避光存放。
Abstract:Sodium alginate was used as wall material and black rice anthocyanin extract was used as core material to make microcapsules by microcapsule granultor.The anthocyanin embedding rate was chosen as detected index,the effects of needle diameter,the ratio of wall and core,sodium alginate concentration and CaCl2concentration on the embedding rate were detected.The optimum conditions were as follows:3 ∶1 wall core ratio,needle diameter of 0.45 mm,sodium alginate concentration of 4.0%,and CaCl2concentration of 3.0%.Meanwhile,the sustained-release properties and stability of black rice anthocyanin microcapsules were investigated.The results showed that microcapsules could exist for 4.0 h in the stomach simulate liquid,and release completely in intestine simulate liquid.It also proved that the anthocyanin microcapsules should be protected from light and atmosphere.
文章编号:202024015 中图分类号: 文献标志码:
基金项目:吉林省教育厅“十三五”科学技术研究项目(JJKH20180519KJ)
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