Abstract:Fucaxanthin is a kind of natural pigment with strong antioxidant activity，which is widely found in algae，shellfish and other animals and plants.It can senescence，anti-tumor，and has high medicinal value.Since kelp was a kind of brown algae rich in fucoxanthin，in order to further develop and utilize fucoxanthin in kelp，the response surface optimization ultrason-assisted enzymatic method was used to extract fucoxanthin and study the influence of different enzymatic hydrolysis conditions on the extraction amount.The results showed that the extraction amount of fucaxanin reached 0.837 5 mg/g under the conditions of enzymatic hydrolysis pH of 5.0，enzymatic hydrolysis time of 71 min and enzymatic hydrolysis temperature of 58℃ obtained by response surface optimization.