Abstract:With the wide application of radioactive technology and nuclear technology in medical，industrial and military fields，radioactive pollution and radiation damage have become factors that endanger human living environment and human health，which cannot be ignored.Corresponding to this，the research of various radiation protective agents has received attention.However，anti-radiation chemical drugs usually have problems such as high research and development costs，and toxic side effects at effective doses.Therefore，the development and application of radioprotectants derived from natural active substances have broader prospects.Based on relevant reports at home and abroad，this paper reviews the research progress of various natural radioprotectants and provides reference for further research as well as development of new natural radioprotectants.