Abstract:The ultrasonic-assisted extraction process of the active constituents in Semen Ziziphi Spinosae was optimized by single factor combined with response surface methodology，and the extract was analyzed by liquid chromatograph-mass spectrometry（LC/MS）.The results showed that at the conditions of 70%ethanol，liquidsolid ratio 25∶1 （mL/g），ultrasonic time 37 min，ultrasonic temperature 50℃ and ultrasonic power 200 W，the extraction amount calculated by jujuboside A was 7.09 mg/g.Liquid chromatography analysis showed that the extract contained 10 triterpenoids，9 flavonoids and 2 alkaloids.The extract was made up of tryptophan and other auxiliary materials to make a solid beverage，and the process conditions were optimized by single factor and orthogonal experiments taking the sensory evaluation as the standard.The results showed that the best formula was：2 g of jujuba extract，0.8 g of maltodextrin，0.8 g of xylitol，0.06 g of citric acid and 0.02 g of sucrose fatty acid ester.The product had good brewing properties，delicate organization and sweet and sour entrance flavor，which would have a good development prospect.