Abstract:Supercritical fluid granular technology is regarded as a promising new micronization technology with many advantages，such as simple operation，controllable particle size，mild treatment conditions and green environmental protection.Carotenoids are a group of natural nutrients that exist widely in nature and have important physiological functions on the human body.Due to their defects such as easy decomposition by oxygen，heat and light，poor water solubility and low bioavailability，their applications have been restricted by various aspects.However，it can be effectively improved by making micropowder or microcapsule through supercritical fluid granular technology.In this paper，the types and operating principles of this technology and its applications on the preparation of carotenoid particles were introduced，and the main factors affecting the preparation of carotenoid particles were also described.Finally，the future development trend was prospected.