Abstract:Aflatoxin is the most toxic and carcinogenic natural pollutant found today.And it not only does great harm to the health of human and animal，but also leads to huge economic losses.The research on the detoxification of aflatoxin has become a hot topic.The biological detoxification of aflatoxin was reviewed，including biosorption，biological enzymolysis and biological extract inhibition method.It is expected that the biological detoxification of aflatoxin could be applied to industrial production，so as to realize its practical application value.