Abstract:Response surface methodology was used to optimize the parameter of pretrement on bagasse by ultrasonic assisted NaOH and ammonia to produce xylose.The single-factor experiment was conducted to explore the effect of mixed double alkali concentration and ratio，ultrasonic time，ultrasonic power，ultrasonic temperature，ratio of solid-liquid on xylose concentration in bagasse hydrolysate.On this basis，optimization model was designed by Box-Behnken design and verification experiment was conducted to inspect comprehensive influ ence of 4 factors on xylose concentration.Optimized conditions was obtained：ratio of NaOH-ammonia was 2∶1（volume ratio），mixed double alkali concentration was 17%，ultrasonic temperature was 45℃，ultrasonic power was 300 W，ultrasonic time was 40 min.The xylose concentration of verifying result was 2.431 0 g/L，which was consistent with the theoretical value of 2.5 g/L.