Abstract:In order to improve the taste and efficacy of Cordyceps militaris extract products，study the production technology of Cordyceps militaris buccal tablet.Using the extractive by ultrahigh pressure treatment combined with cellulase hydrolysis as the raw materials.The best combination of formula was determined by sensory evaluation as the main index，and the quality evaluation and immunological experiment were carried out.The optimum combination formula were extractive of Cordyceps militaris adding amount was 10%，the starch and malt dextrin that taste best adding ratio is 1 ∶1.After examining the moisture，ash content，hardness and tablets quality indicators of the difference of weight，the buccal tablet all accord with the requirement of pharmacopoeia.By animal experiments，respectively by low，medium and high dose of buccal tablets fed mice.The effects of the organ/body weight ratio and mice carbon particle clearance capability and spleen lymphocyte proliferation，comparing with the control group，the mice which is fed with the extract from Cordyceps militaris buccal tablet got higher macrophage phagocytic index，as well as T lymphocyte transformation rate and B lymphocyte transformation rate.This indicates that the ultrahigh pressure assisted enzymatic solution extract from Cordyceps militaris buccal tablets has the function of enhancing the immune.