Abstract:The processing technology of blueberry effervescent tablets which use blueberry powder，citric acid，sodium bicarbonate，sweet chrysanthemum glucoside as raw materials was researched in the present study.The best formula was optimized by single-factor experiment and orthogonal experiment.The research showed that the best formula of chewable was：blueberry powder 5.3%，stevia sugar 3.3%，sodium bicarbonate 39.3%，citric acid 47.1%，polyvinyl pyrrolidone（dissolved by ethanol，concentration was 5%）2.5%，polyethylene glycol 8000 2.5%.The effervescent tablets was prepared by half dry particle method，and the dry conditions was 50℃for 3 h.