Abstract:In order to provide theoretical basis for rationally developing and utilizing Hovenia accrba sticks polyphenols，the extraction technology of polyphenols from Hovenia accrba sticks was optimized by response surface methodology and studying its antioxidant activity.Using Hovenia accrba sticks as experimental materials，the effects of extraction solvent，material-liquid ratio，extraction temperature and extraction time on extraction rates of polyphenols were studied based on single factor experiment with response surface methodology.The antioxidant activities were investigated on the basis of hydroxyl radical，ABTS free radical and DPPH free radical assay．Result showed that the optimal extraction conditions were using anhydrous alcohol as extraction solvent with conditions of material-liquid ratio 1∶84 （g/mL），extraction temperature 60℃，extraction time 2.56 h，and the optimum extraction rate was up to 7.089%.The antioxidant activity tests revealed that polyphenols exhibited antioxidant activities in a concentration-dependent manner，and maximum scavenging rate were 90.97%，93.99%and 97.19%，respectively.