Abstract:The extraction process for polysaccharide in hawthorn was optimized.With water as extraction solvent，the effect of extraction time，extraction temperature and liquid-solid ratio on the yield of polysaccharide were optimized with single factor test followed by response surface methodology.The results of optimal extraction conditions for polysaccharide was given.The solid-liquid ratio was 25∶1（mL/g），temperature was 90℃，the extraction time was 93 min.Under this condition，the extraction yield of hawthorn polysaccharide was 53.77%.The extraction process was simple and reasonable，suitable for industrial production.