Abstract:As a kind of widespread and harmful mycotoxin to human and animal health， patulin is the natural contaminants in fruit and its products， grain and other food products， especially existing in putrid apple and its products. Studies have shown that patulin possesses carcinogenicity， teratogenicity， mutagenicity， immunotoxi－ city， reproductive toxicity and other hazards. At present， the removal technology of patulin were mainly divided into three categories， including physical method， chemical method and biological method. This article summa－ rized the research progress on contamination status， biological toxicity and removal technology of patulin， and provided certain theoretical basis for subsequent research.