Abstract:Four additives with different functional groups were systematic studied on microwave under the ac－ tion of 5 kinds of plastic food packaging film， including antioxidant butylated hydroxytoluene， antioxidant 168， HALS770 and plasticizer DBP. Their migration behaviors in olive oil were studied. The relationship between molecular structure and the migration of compounds was studied base on the various compounds migration rate under different experimental conditions. The four different diffusion coefficient of migration of chemical sub－ stances were calculated using plastic hickness， microwave power， time effect on the rate of migration.