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投稿时间：2016-03-24
投稿时间：2016-03-24
中文摘要: 研究猴头菇多糖的体内抗氧化活性。通过颈背部皮下注射D-半乳糖，制备衰老小鼠模型，测定猴头菇多糖对D-半乳糖小鼠血清及肝脏组织内总超氧化物歧化酶（T-SOD）、丙二醛（MDA）、谷胱甘肽（GSH）及蛋白质羰基含量的影响。结果表明，D-半乳糖衰老模型小鼠血清及肝脏内T-SOD、GSH含量显著降低（P＜0.01），MDA与蛋白质羰基含量明显升高（P＜0.01），猴头菇多糖可以显著提高D-半乳糖小鼠血清和肝脏内T-SOD、GSH含量，降低MDA与蛋白质羰基含量，对D-半乳糖小鼠，猴头菇多糖表现出良好的体内抗氧化作用。
Abstract:To study the antioxidant effects in vivo of polysaccharide from Hericium erinaceus on aging mice induced by D-galactose.Mice were subcutaneous injected with D-galactose at the neck back to establish the aging model，the antioxidant activity in vivo of polysaccharide from Hericium erinaceus was evaluated by measure the contents of T-SOD，MDA，GSH and protein carbonyl in serum and liver tissue.The results showed that the contents of T-SOD and GSH in serum and liver tissue of aging mice induced by D-galactose were reduced significantly（P＜0.01），the contents of MDA and protein carbonyl were increased significantly（P＜0.01），Hericium polysaccharides was effective in improving the the contents of T-SOD and GSH in serum and liver tissue of aging mice induced by D-galactose and reducing the contents of MDA and protein carbonyl，have strong antioxidant activity in vivo.
文章编号：201610014 中图分类号： 文献标志码：
基金项目:
| Author Name | Affiliation |
| WU Mei-yuan，YU Tian-nü，WANG Xi-zhou* | Continuing Education College of Lishui University，Lishui 323000，Zhejiang，China |
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