Abstract:As the most representative core active ingredient in Poria cocos, a medicinal and edible fungus, Poria cocos polysaccharide possesses prominent advantages such as wide vailability, high safety, low toxicity, and diverse biological activities, demonstrating significant research and application value in the fields of food, medicine, and agriculture. This paper reviews the latest resea progress of Poria cocos polysaccharide in recent years regarding extraction process optimization, separation and purification techniques, structural characterization, exploration of multiple biological activities, modification, and applications, anmmarizes the key technologies and research findings in each aspect. On this basis, the existing problems in the research of Poria cocos polysaccharides are analyzed, and the future research direction are prospected, in order to provide scientific reference and theoretical support for the in-depth development, efficient utilization and industrial production application of Poria cocos polysaccharide.