Abstract:An inductively coupled plasma mass spectrometry （ICP-MS） method was established for the determination of 16 rare earth elements （REEs） in livestock and poultry meat.The samples were treated by microwave digestion and qualified by ICP-MS using the internal standard method.Under the optimal instrument conditions （radio frequency power：1 600 W,plasma gas flow rate：18.0 L/min,auxiliary gas flow rate：1.2 L/min,atomization gas flow rate：1.06 L/min,peristaltic pump speed 20 r/min）,the 16 rare earth elements exhibited good linearity,with the correlation coefficients all greater than 0.999,when the concentration range was 0-20 μg/L.The limits of detection （LODs） ranged from 0.05 to 0.30 μg/kg.The spiked recovery rates were 82.4%-106.7%,and the relative standard deviations （RSDs） ranged from 0.11% to 5.56%.The measured values of 16 rare earth elements in chicken,as specified in the national standard reference material GBW10018,were consistent with the standard reference values.In conclusion,the method has simple sample processing and high detection sensitivity,and is suitable for the determination of 16 rare earth elements in livestock and poultry meat.