Abstract:To prepare a high dietary fiber meal replacement powder with both gastrointestinal function regulation and weight reduction effects，this study used oat powder，quinoa powder，buckwheat powder，and konjac powder as grain raw materials to determine the optimal ratio of basic grain powder through grade consistency testing.The main raw materials for regulating gastrointestinal function were mixed powder（Codonopsis pilosula∶hawthorn∶tangerine peel=1∶1∶1，mass ratio），which was derived from medicinal and food sources，combined with soy protein isolate，defatted milk powder，xylitol，sucralose，and apple powder. Sensory evaluation was used as an indicator to determine the optimal amount of raw materials and excipients in meal substitutes through single-factor experiments and response surface methodology experiments. The results showed that the optimal formula for meal replacement powder was 8.86 g of oat powder，13.29 g of quinoa powder，4.43 g of buckwheat powder，4.43 g of konjac powder，10 g of soy protein isolate，8 g of skimmed milk powder，2 g of mixed powder，4.87 g of xylitol，0.019 2 g of sucralose，and 3.92 g of apple powder.The meal replacement powder under this formula exhibited a bright color，rich grain aroma，and a mellow taste. The protein，fat，and dietary fiber content were 24.36，2.30 g/100 g，and 38.06 g/100 g，respectively. The measurement results of powder properties showed that the solubility and hydration ability of this generation of meal powder were good，the fluidity was average，and it was not easy to splash. The texture measurement after blending showed that the meal powder had a certain surface hardness，moderate consistency，and low viscosity. The meal replacement powder produced was rich in high dietary fiber and can regulate gastrointestinal function.