Abstract:To explore the auxiliary hypolipidemic effect of Polygonatum cyrtonema，Hawk tea and their combination on hyperlipidemia mice.According to their body weight，mice were randomly divided into blank control group（NC）、model group（MC）、positive control group（PC），low（HLD），medium（HLZ）and high dose group（HLG）of P.cyrtonema-Hawk tea；low（HD），medium（HZ）and high dose group（HG）of P.cyrtonema；low（LD），medium（LZ）and high dose group（LG）of Hawk tea.The mice in the NC group were given basic feed，while those in other groups were given high-fat feed and given the corresponding drug solution by gavage at the same time.After continuous administration for eight weeks，serum and liver were collected to determine total cholesterol，triglyceride，high-density lipoprotein cholesterol，low-density lipoprotein cholesterol，aspartate aminotransferase，alanine aminotransferase，superoxide dismutase，malondialdehyde，and glutathione peroxidase in each group of mice.The results showed that compared with the model group，P.cyrtonema and Hawk tea both had an auxiliary hypolipidemic effect and a certain protective effect on the liver，and the effect was better after they were combined.