Abstract:Salmonella，a common group of foodborne pathogenic bacteria，induces enteritis and systemic infection，seriously endangering human health.The priorities of research on Salmonella include quick detection of the bacteria and prevention of the related diseases.Being able to bind to specific targets，the nucleic acid aptamers of Salmonella can be used as recognition elements to assist detection or as targeting tools to improve the delivery efficiency of bactericidal drugs.In addition，aptamers can bind to the active structure to inhibit the biological activity and reduce the risk of Salmonella to human health，demonstrating great potential in both the detection and control of Salmonella.The sequences and screening methods of Salmonella aptamers，the application of the biosensors with aptamers as recognition elements in the rapid detection of Salmonella，and the antibacterial mechanisms and therapies of Salmonella aptamers were summarized，with a view to providing references for further research and application of antibacterial aptamers.