Abstract:ε-Polylysine（ε-PL），an efficient，green and safe natural substance with excellent antibacterial activity，biodegradability，stability and safety，is increasingly applied in food industry.It mainly exerts the antibacterial effect by affecting cell membrane，enzymes，proteins，and genetic materials.Adding ε-PL to food can inhibit the growth of bacteria and delay the decay，thereby extending the shelf life of food.In recent years，the composite preservation technology combining ε-PL with other preservation technologies has become a hot spot in the research on meat preservation.The research progress in the antibacterial mechanism of ε-PL and the application of ε-PL combined with other preservation technologies（composite preservatives，composite coatings，composite nanofibers，etc.） in the preservation of meat products were reviewed.This review is expected to provide a basis for the in-depth research and application of ε-PL in the preservation of meat products in the future.