Abstract:The purpose of the study was to develop an accurate and rapid method for the determination of malondialdehyde（MDA）in meat and meat products.Based on trichloroacetic acid（TCA）extraction and 2-thiobarbituric acid （TBA）reaction，quantitative analysis of MDA in meat and meat products was conducted using ultra-performance liquid chromatography with fluorescence detection（UPLC-FLD）and ultra-performance liquid chromatography with diode array detection（UPLC-DAD）methods.The results showed that the content of MDA in most meat products was similar，except in cooked ham and Frankfurt sausage，when determined by the two UPLC methods.However，the content of MDA detected through thiobarbituric acid reactive substances（TBARS）spectrophotometry was higher than the actual thiobarbituric acid reactant content.Therefore，these two chromatographic methods，especially the UPLC-FLD method，were more accurate than the traditional TBARS method.They enabled accurate detection of the MDA content in meat products and helped avoid the use of the contaminated meat.