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食品研究与开发:2021,42(15):198-203
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蛋白基姜黄素纳米颗粒递送体系研究进展
(1.许昌学院食品与药学院,河南 许昌 461000;2.河南省食品安全生物标识快检技术重点实验室,河南 许昌 461000;3.黄淮学院生物与食品工程学院,河南 驻马店 463000)
Research Progress of Protein-based Curcumin Nanoparticle Delivery System
(1.College of Food and Medicine,Xuchang University,Xuchang 461000,Henan,China;2.Key Laboratory of Biomarker Based Rapid-detection Technology for Food Safety of Henan Province,Xuchang 461000,Henan,China;3.College of Biotechnology and Food Engineering,Huanghuai University,Zhumadian 463000,Henan,China)
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投稿时间:2020-08-28    
中文摘要: 姜黄素是一种具有抗氧化、抗菌以及抗癌等多种生物活性的疏水性植物多酚。因存在水溶性差、不稳定、易分解以及在体内代谢快和生物利用度低的问题,姜黄素作为功能性食品配料的应用受到了限制。食品胶体递送体系是一种利用食品组分间相互作用,通过构建食品胶体微结构实现对食品功能因子包埋、保护及控释的技术。以蛋白质为载体构建的姜黄素复合纳米颗粒胶体递送系统能够为姜黄素在功能食品中的应用提供一种有效途径。该文介绍当前蛋白基姜黄素复合纳米颗粒的制备方法,并详细阐述不同蛋白质(动物蛋白、植物蛋白以及蛋白水解物)在构建姜黄素复合纳米颗粒中的应用,以期为姜黄素在功能性食品中的应用提供参考。
Abstract:Curcumin is a hydrophobic plant polyphenol with antioxidant,antibacterial and anticancer activities.The application of curcumin as a functional food ingredient is limited because of its poor water solubility,instability,easy degradability,rapid metabolism in vivo,and low bioavailability.Food colloidal delivery system is a technology that embeds,protects and controls the release of food functional components by constructing appropriate food colloidal microstructures.Protein-based colloidal delivery system can provide an effective way for the application of curcumin in functional foods.The current methods of preparing protein-based curcumin composite nanoparticles were presented.The applications of different proteins(animal,plant and hydrolysate proteins)in constructing curcumin composite nanoparticles were reviewed in detail,to provide a reference for the application of curcumin in functional foods.
文章编号:202115030     中图分类号:    文献标志码:
基金项目:河南省自然科学基金项目(202300410347);河南省高等学校重点科研项目(21A550011)
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