Abstract:Compound amino acid zinc and iron were prepared from 8 kinds of essential amino acids by waterbased synthesis.The antimicrobial activities of two-fold test tube dilutions of Lysinibacillus macrolides，Bacillus cereus，Bacillus subtilis，Staphylococcus aureus，Pseudomonas aeruginosa，Escherichia coli，Zygosaccharomyces rouxii，Saccharomyces cerevisiae，Aspergillus flavus，Penicillium expansum，and Aspergillus niger were determined.The clearance rates of DPPH·，O2-·，and·OH were also determined.The rates of zinc and iron chelation were 81.27% and 68.19%，respectively.Both displayed significant antimicrobial activity against the tested bacteria and yeasts.The inhibition of B.subtilis and S.aureus was the most significant，with a minimum inhibitory concentration of 0.313 mg/mL.No significant inhibition of the tested molds was evident.Compound amino acid zinc and iron scavenged DPPH·，O2-·，and·OH radicals in a concentration-dependent manner.The respective clearance rates of 2.5 mg/mL compound amino acid zinc and iron were 34.52%，23.93%，and 22.36% for compound amino acid zinc and 30.46%，20.63%，20.05% for compound amino acid iron.