Abstract:Acipenser gueldenstaedti Brandt was used as the raw material to screen and optimize the conditions of degreasing with lipase. By comparing the muscle degreasing rate and protein loss rate before and after degreasing processing,the optimal degreasing conditions were as follows: the enzyme concentration was 20 U/mL,pH 9 and soaking time was 50 min. Furthermore, the analysis of fatty acid composition, tissue morphology, fat distribution, fishy compound of fish meat with and without degreasing showed that enzymatic degreasing had certain damages to the sturgeon muscle tissue structure,it was reducing fishy compounds and maintain nutrition simultaneously,it could obviously achieve degreasing effect.