Abstract:Ultra performance liquid chromatography quadrupole time-of-flight-tandem mass spectrometry（UPLC-Q-TOF-MS/MS）was used to identify the chemical components of Choerospondias axillaris fruit peel wine.The contents of total flavonoids，total proanthocyanidins，and total phenols in C.axillaris fruit peel wine were determined by ultraviolet spectrophotometry.Antioxidant and α-glucosidase inhibition activity experiments were also carried out in vitro.By comparing with some reference substances，liquid chromatography-tandem mass spectrometry（LC-MS/MS）fragment information and literature data，a total of 34 compounds were identified in C.axillaris fruit peel wine.The results showed that C.axillaris fruit peel wine mainly contained flavonoid glycosides，proanthocyanidin oligomers，phenols，organic acids and esters.The contents of total flavonoids，total phenols，and total procyanidins were 15.239，7.595，4.015 mg/mL，respectively.The IC50values of C.axillaris fruit peel wine in scavenging DPPH free radical and inhibiting α-glucosidase were 2.656，10.996 mg/mL，respectively.The results showed that C.axillaris fruit peel wine had good antioxidant and α-glucosidase inhibition activities，suggesting C.axillaris fruit peel wine had better health care function.The results of this study provided data support for the development of high value-added products such as C.axillaris fruit peel wine and the comprehensive utilization of C.axillaris fruit peel waste.It also provided idea for the comprehensive development and utilization of similar traditional Chinese medicine waste.