Abstract:The study was aimed to understand the stability of functional components in asparagus extracts and to explore the anti-fatigue function of the extracts in mice.Accelerated destructive test was conducted for 3 months to determine the content of total saponins，polysaccharides，and total flavonoids at 0 months（before placement），1 month，2 months and 3 months.ICR mice were randomly divided into 4 groups，namely the negative control group and 3 dosage groups[0.5，1.0，1.5 g（/kg·d）].After continual intragastric administration for 30 days，the time of weight-loading swimming，hepatic/muscle glycogen content under normal condition，serum urea after exercise，blood lactic acid/glucose before and after exercise were detected.Results showed that the extracts had good stability as the content of total saponins and polysaccharides in asparagus extracts had no significant changes.The asparagus extracts could extend the time of weight-loading swimming，increase the hepatic glycogen and muscle glycogen content and decrease the area under curve of the blood lactic acid and the blood glucose reduction.Thus，the asparagus extracts had obvious anti-fatigue function and the mechanisms were related to the increase of glycogen storage in the body，the acceleration of lactic acid metabolism and the recovery of blood glucose level.