Abstract:The nutrient profiles of different muscle zones were determined for sturgeon hybrids of Huso dauricus and Acipenser schrenckii and the muscles of the hybrid sturgeon were finely divided.The distribution pattern of their proximate compositions，amino acids，fatty acids and minerals in different zones of the hybrid sturgeon were analyzed.The fat content was found increased first and then decreased from head to tail direction，ranging from 3.31% to 6.70%，being highest in posterior dorsal.The contents of moisture and protein were inversely proportional to fat content.Similar tendencies in amino acid and fatty acid profiles were also found from head to tail.Umami amino acids were found gradually decreased first and then increased from head to tail.Monounsaturated fatty acid（MUFA）was the most abundant fatty acid found in all zones，ranging from 37.32% to 39.80%，followed by polyunsaturated fatty acids（PUFA）ranged from 30.97% to 35.36% of total fatty acid.Posterior tail showed the highest docosahexaenoic acid（DHA）proportion.In addition，the hybrid sturgeons are rich in mineral elements and the highest Fe and Zn content were found in the posterior tail.This study revealed that chemical compositions in giant hybrid sturgeon varied regularly amongst different zones.