Abstract:The incidence of foodborne diseases has increased over the years and resulted in major public health problem globally.Foodborne pathogens can be found in various foods and it is important to detect foodborne pathogens to provide safe food supply and to prevent foodborne diseases.The traditional bacterial detection method is complex and time-consuming；therefore，it is necessary to establish a rapid and convenient detection method that can detect multiple pathogens simultaneously.Nucleic acid detection of foodborne pathogens has been widely used in the detection of foodborne pathogens because of its simple operation，short timeconsuming，high specificity and high sensitivity.Therefore，This review will focus on recent rapid detection methods based on nucleic acids，including conventional polymerase chain reaction （PCR），multiplex PCR，real-time PCR，loop-mediated isothermal amplification（LAMP）；polymerase spiral reaction（PSR）；recombinase polymerase amplification （RPA）.The advantages and disadvantages as well as the applicable scope are summarized to provide certain theoretical basis for developing simple，fast，effective and accurate detection methods.