Abstract:Food nutrition and safety is closely related to people's health. The application of modern food processing technology can reduce the loss of nutrients in food processing and food preservation，and can also improve the nutritional value and absorption rate of food，minimize the proliferation of microorganisms that cause food spoilage. Microemulsion technology is a new technology with wide application. The microemulsion system prepares by using food grade components can protect bioactive components in foods，improve the digestibility and antioxidative ability of food components，enhance the antibacterial effect of food ingredients，prevent foodborne diseases caused by microbial contamination of food，and improve food safety. Microemulsion technology can also be used as a technical means for food separation and detection.In this paper，the structure，preparation and application of microemulsion in bacteriostatic，aid digestion，antioxidant，encapsulated food functional active ingredients，microemulsion electrokinetic chromatography and other aspects were reviewed.The application prospect of microemulsion in the field of food nutrition and safety was also prospected in this paper and provided a reference for the further research of this technology in food field.