Abstract:The aim of the present study was to investigate the effect of Rose roxbunghii，hawthorn and mung bean beverage as main raw materials on hyperlipidemia.The model of hyperlipidemia was induced by intragastric administration of high-fat diet，and the model was successfully established in 4 weeks.The successful mice were divided into three groups：high-fat model control group，positive control group，and Rose roxbunghii，hawthorn and mung bean beverage group.The blank group and the model control group were intragastrically administered with normal saline，the positive control group was intragastrically administered with simvastatin solution，and Rose roxbunghii hawthorn mung bean group was given the Rose roxbunghii，hawthorn and mung bean beverage，both of which drank distilled water.At the same time，the body weight and feed intake of the mice were measured during the intragastric administration to calculate the body weight gain and feed efficiency of the mice.After 28 days of continuous gavage，the levels of total cholesterol（TC），triglyceride（TG）and highdensity lipoprotein （HDL-C）in serum and liver of mice were measured to evaluate the hypolipidemic effect.Results showed that the serum TC significance （p＜0.05）of Rose roxbunghii hawthorn mung bean beverage group decreased by 42.24 %.Serum and liver TG content was significantly （p＜0.05）decreased by 24.12%，46.24%.The serum and liver HDL-C levels were significantly increased （p＜0.05）by 21.96%，77 %.These indicated that Rose roxbunghii hawthorn mung bean beverage could achieve blood lipid lowering by regulating blood lipid balance.