Abstract:In order to optimize the ultrasonic extraction of anthocyanins from fruit of Rubus coreanus Maq.，response surface methodology was used to optimize the extraction process of anthocyanins with four impact factors of ultrasonic power，extraction time，ethanol concentration and solid-to-liquid ratio.Anthocyanin yield was the evaluation index to investigate anthocyanin extraction process from fruit of Rubus coreanus Maq..Results indicated that the optimal extraction conditions of anthocyanins from fruit of Rubus coreanus Maq.was ultrasonic power of 141 W，extraction time of 22.60 min，ethanol concentration of 74.50%（pH 2），solid-toliquid ratio of 1∶40（g/mL）.Under the optimal extraction conditions，the anthocyanin yield from fruit of Rubus coreanus Maq.was 263.15 mg/100 g，it was higher than that of 211.05 mg/100 g extracted by mechanical shaking extraction.Therefore，the ultrasonic assisted extraction technology was conducive to the extraction of anthocyanin components than the method of mechanical shaking extraction，and the process had shorter time and higher efficiency compared with the control group.