Abstract:The crude extract of blueberry pomace was subjected to simulated gastrointestinal digestion in vitro，to determine changes in the release of active antioxidant substances and antioxidant capacity，in order to provide references for development and utilization of blueberry pomace resources.The blueberry peel residue as raw materials were studied to simulated gastrointestinal digestion in vitro for the research of anthocyanin，polyphenols and flavonoids content，and antioxidant activity was made.The results showed that after simulated gastric digestion，antioxidant activity and polyphenol，flavonoid，anthocyanin contents of crude extract of blueberry pomace increased significantly （p＜0.05）.The amount of released polyphenol reached a maximum level during the 30 min gastrointestinal digestion.But the anthocyanin and polyphenol flavonoids of control group did not change significantly （p＞0.05）.The chemical environment of the gastrointestinal tract plays no auxo－action on the release of polyphenol，but the digestive enzymes have a significant auxo－action on the release of crude extract flavnoids.In the simulated intestinal digestion process，the active antioxidant substances and antioxidant capacity reached a maximum level during 2 h－3 h，but the antioxidant activity lower than that of simulated gastric digestion，possibly because of the polyphenols and anthocyanin content decreased.This study will provide basis for the improvement for the added value of blueberry pomace processing as well as the development of functional food.